Publications

Detailed protocols for the experimental and computational pipelines used by the Chain lab for TCR repertoire analysis using the Decombinator software platform. - I. Uddin, A. Woolston, T. Peacock et al, Quantitative analysis of the T cell receptor repertoire, Methods in Enzymology 629, 465-492 (2019).

Analysis of the TCR repertoire in non-small-cell lung cancer (NSCLC), examining the correlation between TCR abundance and the number of mutations found in subdivided tumor regions - K. Joshi, M. Robert de Massy, M. Ismail et al. Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer. Nature Medicine 25, 1549–1559 (2019).